"Driven
by nearly 20 years of pioneering research and innovation, StemCells is a
recognized leader when it comes to expertise, scientific achievement and
intellectual property in the field of stem cell biology."
"StemCells,
Inc. is applying its scientific and industry leadership in stem cell biology
to discover, develop and commercialize breakthrough therapeutics and
enabling tools and technologies for use in stem cell-based research and drug
discovery."
Overview
StemCells (STEM)
a biopharmaceutical company, engages in the research, development, and
commercialization of stem cell therapeutics, and related tools and
technologies for academia and industry.
It develops cell-based therapeutics
for the central nervous system and liver. The company's product candidate
HuCNS-SC cells has completed a Phase I clinical trial for the treatment of
infantile and late infantile neuronal ceroid lipofuscinosis, a
neurodegenerative disorder of the brain; and completed a Phase I clinical
trial for the treatment of Pelizeaus-Merzbacher disease, a fatal myelination
disorder in the brain. It also engages in developing HuCNS-SC cells, which
are in Phase I/II clinical trial for the treatment of chronic spinal cord
injury; and HuCNS-SC cells that are in Phase I/II clinical trial for the
treatment of dry age-related macular degeneration.
In addition, the company identifies
and develops human liver engrafting cells for a range of liver diseases; and
is involved in developing and commercializing applications of its
technologies to enable stem cell-based research. Further, it markets a range
of proprietary cell culture products under the SC Proven brand, including
iSTEM, GS1-R, GS2-M, RHB-A, RHB-Basal, NDiff N2B27, NDiff N2, and NDiff N27
supplements, as well as HEScGRO and ESGRO Complete; and antibody reagents
under the SC Proven brand comprising STEM24, STEM101, STEM121, and STEM123
for cell detection, isolation, and characterization. The company sells its
tools and technologies products to researchers at academic institutions,
pharmaceutical and biotechnology companies, and government laboratories.
STEM
Investor Highlights
Partnered
with R Biomedical, an Edinburgh, UK-based biomedical company, to develop
and commercialize a range of cell lines and reagents to facilitate human
induced pluripotent stem (iPS) cell-based research for regenerative
medicine applications. The first product under the partnership, an
"ultra-primary" human fibroblast cell line from which
researchers can generate iPS cell lines, was launched today under the SC
Proven brand.
StemCells
has a broad and expanding clinical development program for its HuCNS-SC
cells. The Company has ongoing Phase I/II clinical trials in chronic
thoracic spinal cord injury and dry age-related macular degeneration,
and is planning for a controlled Phase II study in Pelizaeus-Merzbacher
Disease.
Announced
the issuance of U.S. Patent Number 8,283,164 titled "Liver
engrafting cells, assays, and uses thereof." The patent broadly
covers purified populations of human liver cells, including the
Company's human liver engrafting cells (hLEC). hLEC cells were first
isolated by Company researchers in the late 1990s, and Company
scientists have repeatedly demonstrated the cells' engraftment and
robust bioactivity in vivo and that they are expandable.
In October
2011, StemCells formed a wholly-owned subsidiary to focus on both the
therapeutic and research tool applications of its hLEC technologies and
to serve as an investment vehicle for those interested in a "pure
play" liver cell company.
Martin
McGlynn - President and Chief Executive Officer
Martin McGlynn joined StemCells, Inc. in
January of 2001 as President and Chief Executive Officer and was elected to
our Board of Directors on February 6, 2001. Mr. McGlynn has spent several
decades in the life sciences industry in Europe, Canada and the United
States. He began his career with Becton Dickinson, Ireland Ltd., and spent
eight years in manufacturing operations. He joined Abbott Labs in 1977 where
he held positions as General Manager, Abbott Ireland Ltd., President and
General Manager of Abbott Canada Ltd. and Vice President of Abbott
International Ltd. In 1990, he joined the BOC Group as President of Anaquest,
Inc., a global leader in anesthesia and acute care pharmaceuticals
headquartered in New Jersey. Mr. McGlynn joined the biotech industry in 1994
when he became President and Chief Executive Officer of Pharmadigm, Inc., a
private, venture capital-backed company engaged in the research and
development of a new class of anti-inflammatory agents. Mr. McGlynn is a
native of Dublin, Ireland. He holds a Bachelor of Commerce degree from
University College, Dublin. He is a former member of the Board of Directors
of the Confederation of Irish Industries (CII) and the Pharmaceutical
Manufacturers Association of Canada (PMAC), and currently serves as a member
of the Board of the Alliance for Regenerative Medicine (ARM).
Ann
Tsukamoto PhD. - Executive Vice President, Research and Development
Ann Tsukamoto was appointed Executive Vice
President, Research and Development in September 2008. She previously served
as Vice President, Research and Development. Dr. Tsukamoto has more than 20
years experience in stem cell biology and was a co-discoverer of the human
hematopoietic stem cell while at SyStemix, Inc., and played a leading role
in the launch of the clinical research program for the hematopoietic stem
cell. Under her direction at StemCells, Inc., the scientific team isolated
the human neural stem cell, a population of human liver engrafting cells and
a candidate pancreas stem cell. Dr. Tsukamoto received her PhD from the
University of California, Los Angeles and did postdoctoral research with Dr.
Harold Varmus at the University of California, San Francisco where she
worked on the wnt-1 gene, which is a key player in the stem cell
self-renewal pathway. Dr. Tsukamoto is an inventor on six issued US patents
related to the human hematopoietic stem cell.
Rodney
Young - Chief Financial Officer and Vice President, Finance and
Administration
Rodney Young joined StemCells, Inc. in
September 2005. He has overall responsibility for corporate financial
management, financial reporting and controls, investor relations and
information technology. Prior to joining StemCells, Mr. Young was Chief
Financial Officer and a director of a private pharmaceutical company focused
on developing drugs for pediatric indications, where he was responsible for
all financial and administrative functions. Before joining the biotechnology
industry, Mr. Young was Managing Director and head of health care corporate
finance in Europe for SG Cowen Securities, and prior to that, he spent more
than a decade at Lehman Brothers, where he was a senior investment banker in
both the health care and mergers & acquisitions groups. Mr. Young earned
his BA and MBA degrees from the University of Chicago.
7707 Gateway Boulevard
Suite 140
Newark, CA 94560
Phone: 510-456-4000
Fax: 510-456-4001
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